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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRK
All Species:
10.3
Human Site:
S92
Identified Species:
18.89
UniProt:
P42685
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42685
NP_002022.1
505
58254
S92
L
E
K
R
R
D
G
S
S
Q
Q
L
Q
G
Y
Chimpanzee
Pan troglodytes
XP_518702
505
58217
S92
L
E
K
R
Q
D
G
S
S
Q
Q
L
Q
G
Y
Rhesus Macaque
Macaca mulatta
XP_001112190
505
58228
S92
L
E
K
R
R
D
G
S
S
Q
Q
L
Q
G
Y
Dog
Lupus familis
XP_539091
505
57709
G96
A
R
R
L
D
G
R
G
E
G
R
P
Q
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q922K9
512
58825
L99
L
E
K
K
G
T
G
L
G
Q
Q
L
Q
G
Y
Rat
Rattus norvegicus
Q62662
506
58147
L93
L
E
K
K
G
P
G
L
G
Q
Q
L
Q
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02977
536
59984
L124
D
W
W
E
A
R
S
L
S
S
G
A
T
G
Y
Frog
Xenopus laevis
P13406
537
60828
L125
D
W
W
E
A
R
S
L
T
T
G
G
T
G
Y
Zebra Danio
Brachydanio rerio
XP_695937
480
54879
Y90
S
L
D
A
E
P
W
Y
F
P
E
T
K
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
K106
D
W
W
L
A
R
S
K
K
T
R
S
E
G
Y
Honey Bee
Apis mellifera
XP_396043
451
51726
Y65
I
F
V
A
L
Y
D
Y
D
A
R
T
D
E
D
Nematode Worm
Caenorhab. elegans
NP_493502
507
57512
K100
D
W
W
F
A
R
H
K
A
T
G
R
T
G
Y
Sea Urchin
Strong. purpuratus
NP_001135852
530
59779
R120
D
W
W
L
A
R
S
R
L
T
G
L
E
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.6
80.5
N.A.
88.6
88.3
N.A.
N.A.
48.5
48.4
60.5
N.A.
56.8
51.6
50.4
56.6
Protein Similarity:
100
99.8
98
87.7
N.A.
92.9
93
N.A.
N.A.
64.7
64.2
74
N.A.
73.3
67.1
69.4
70.5
P-Site Identity:
100
93.3
100
20
N.A.
66.6
66.6
N.A.
N.A.
20
13.3
0
N.A.
13.3
0
13.3
20
P-Site Similarity:
100
100
100
33.3
N.A.
73.3
73.3
N.A.
N.A.
20
20
13.3
N.A.
26.6
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
39
0
0
0
8
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
0
8
0
8
24
8
0
8
0
0
0
8
0
8
% D
% Glu:
0
39
0
16
8
0
0
0
8
0
8
0
16
8
0
% E
% Phe:
0
8
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
16
8
39
8
16
8
31
8
0
85
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
39
16
0
0
0
16
8
0
0
0
8
0
0
% K
% Leu:
39
8
0
24
8
0
0
31
8
0
0
47
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
16
0
0
0
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
39
39
0
47
0
0
% Q
% Arg:
0
8
8
24
16
39
8
8
0
0
24
8
0
8
0
% R
% Ser:
8
0
0
0
0
0
31
24
31
8
0
8
0
0
8
% S
% Thr:
0
0
0
0
0
8
0
0
8
31
0
16
24
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
39
39
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
16
0
0
0
0
0
0
85
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _